Er no.. what do you mean?
PowerFC was the most common option before nistune came along which is why most people have it, not cos its JDM tyte "look at my ECU"....... which you can't see cos it's behind a kick panel. It offers stuff like a higher tuning resolution, hand controller and display for on the fly adjustments and diagnostics, if you get a d-jetro it'll let you remove the afm, if you get pro you can have two step.
Having said that, nistune is bang for bucks that can get the car going decently. In the future if you want advanced features or motorsport features is where it's limitations will appear so plan ahead and do it once, do it right.